January 1, 1991The Journal of PhysiologyOpen Access

Characteristics of sympathetic preganglionic neurones in the lumbar spinal cord of the cat.

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Population

297 sympathetic preganglionic neurones in the 2nd and 3rd lumbar segments of anaesthetized cats

Design

Preclinical

Authors

MGMichael P. GilbeyUniversity College London RSReuben D. SteinMedical Council of Canada

Discussion

Member takes

Implication

Reveals heterogeneous 5-HT responses among sympathetic neurones; leaves open translation to human cardiovascular regulation.

Structured PICO

Population

297 sympathetic preganglionic neurones in the 2nd and 3rd lumbar segments of anaesthetized cats

Intervention

Ionophoretic application of 5-HT and glutamate, and noxious stimuli to the ipsilateral hindlimb

Outcome

Electrophysiological characteristics including axonal conduction velocities, firing patterns in relation to ECG and phrenic nerve activity, and responses to noxious stimuli and 5-HTsurrogate

Lumbar sympathetic preganglionic neurones in cats are a heterogeneous population with distinct physiological properties and responses to 5-HT that may relate to their specific functions.

Cite This Study

Gilbey et al. (1991) studied this question.

synapsesocial.com/papers/6a8adb161692ae2bc0f449cd https://doi.org/10.1113/jphysiol.1991.sp018392

View Full Paper

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Bookmark

Characteristics of sympathetic preganglionic neurones in the lumbar spinal cord of the cat.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Characteristics of sympathetic preganglionic neurones in the lumbar spinal cord of the cat.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider