Why the study?
To characterize the impact of hypertension on subclinical and clinical changes in a STEMI population.
Does a history of hypertension impact in-hospital outcomes in patients presenting with STEMI?
Does a history of hypertension impact in-hospital outcomes in patients presenting with STEMI?
Despite having more extensive coronary disease and diabetes, STEMI patients with a history of hypertension had lower in-hospital mortality and less acute heart failure, potentially due to prior antihypertensive therapy.
Objective: To characterize the impact of hypertension on a ST elevation myocardial infarction (STEMI) population. We studied both suclinical and clinical changes Results: We reviewed the 2018 data from a geographical region of a national STEMI registry We analized 3800 patients admitted with STEMI in the primary PCI network hospitals. We interogated the national STEMI registry. The in-hospital data were analyzed. We selected the patients with history of hypertension at the moment of acute coronary syndrome diagnosis. Among those 3800 patients analyzed, 2708 (70.9%) had diagnosis of hypertension prior to STEMI. The hypertensive STEMI patients had extensive coronary involvement (31.6 vs. 11.6%, p < 0.005 multivessel disease). Among cardiovascular risk factors, the incidence of diabetes mellitus (DM) was three times higher in the hypertensive group (31.2 vs. 11.6%, p < 0.005); renal impairment and lower hemoglobin levels were noted in this group. The clinical picture at admission in the hypertensive cohort was less severe, with less acute heart failure (class Killip 3 and 4) (9.3 vs. 13.6%, p < 0.005) and lower death rate (5.9 vs.7.7%, p < 0.044). The overall death rate in our cohort was 6.9%, similar with the vast majority of other european cohorts. Conclusions: Though more severe in terms of multiple vesell involvement and cardiac risk factors, the evolution of the hypertensive patients was better probably due to the antihypertensive previous treatment
No takes yet. Share an insight, caveat, or question.
Vintila et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: