What question did this study set out to answer?

To evaluate the technical feasibility of treating abdominal aortic aneurysms using a transfemorally placed intraluminal stent-graft bypass.

July 1, 1992Radiology

Intraluminal bypass of abdominal aortic aneurysm: feasibility study.

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Preclinical study demonstrates successful intraluminal exclusion of aortic aneurysms in dogs, indicating the feasibility of endovascular repair.

To evaluate the technical feasibility of treating abdominal aortic aneurysms using a transfemorally placed intraluminal stent-graft bypass.
Surgically created artificial abdominal aortic aneurysms using fusiform Dacron conduits in 8 dogs.
Delivered a weft-knit Dacron graft flanked by balloon-expandable stents transfemorally through a 14-F sheath and expanded it within the aneurysm using a coaxial balloon.
Evaluated graft patency, structural integrity, and tissue integration through postplacement aortography and histopathologic analysis over a 6-month follow-up.
Immediate exclusion of the aneurysm lumen was achieved in all cases, though graft torsion caused early occlusion in 2 dogs.
Graft patency was sustained in 6 dogs at 6 months, with 4 displaying graft kinking attributed to external aneurysm shrinkage.
Histopathologic analysis revealed complete endothelialization on the stent components and partial endothelialization across the graft surface.

Laborde et al. (1992) studied this question.

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Preclinical study demonstrates successful intraluminal exclusion of aortic aneurysms in dogs, indicating the feasibility of endovascular repair.