Why the study?
Does hyperventilation timing affect the provocation of Prinzmetal's variant angina, and do calcium blockers prevent this response?
Population
1 57-year-old male with Prinzmetal's variant angina, formerly complicated by ventricular fibrillation.
Comparison
Hyperventilation test for 6 minutes performed in… vs Hyperventilation test performed later in the day.
Design
Case_report
Authors
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Hypothesis-generating for time-specific provocation in variant angina; leaves open calcium blocker efficacy beyond this single case.
Does hyperventilation timing affect the provocation of Prinzmetal's variant angina, and do calcium blockers prevent this response?
Hyperventilation in the early morning is an effective provocation test for Prinzmetal's variant angina, and its effects can be prevented by calcium channel blockers.
Mortensen et al. (1981) studied this question.
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