Why the study?
Does prolonged hyperventilation provoke coronary vasospasm in patients with Prinzmetal's variant angina?
Population
n=14 (6 patients with a clinical diagnosis of Prinzmetal's variant angina and 8 control patients)
Comparison
Prolonged hyperventilation test (HVT) vs Control patients without Prinzmetal's variant…
Design
Case-control
Authors
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HVT may support noninvasive diagnosis of Prinzmetal angina; hypothesis-generating in small case-control study and requires prospective validation.
Does prolonged hyperventilation provoke coronary vasospasm in patients with Prinzmetal's variant angina?
Prolonged hyperventilation is an effective non-pharmacological provocation test for diagnosing Prinzmetal's variant angina and assessing the efficacy of drug treatment.
Mortensen et al. (1983) studied this question.
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