Answers are grounded in this paper and cite their sources.
BACKGROUND: To investigate the effects of methylphenidate (MPH) on components of working memory (WM) in attention-deficit hyperactivity disorder (ADHD) and determine the responsiveness of WM measures to MPH. METHODS: Participants were a clinical sample of 50 children and adolescents with ADHD, aged 6 to 16 years old, who participated in an acute randomized, double-blind, placebo-controlled, crossover trial with single challenges of three MPH doses. Four components of WM were investigated, which varied in processing demands (storage versus manipulation of information) and modality (auditory-verbal; visual-spatial), each of which was indexed by a minimum of two separate measures. RESULTS: MPH improved the ability to store visual-spatial information irrespective of instrument used, but had no effects on the storage of auditory-verbal information. By contrast, MPH enhanced the ability to manipulate both auditory-verbal and visual-spatial information, although effects were instrument specific in both cases. CONCLUSIONS: MPH effects on WM are selective: they vary as a function of WM component and measurement.
No takes yet. Share an insight, caveat, or question.
Bedard et al. (2007) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: