Key result
Laparoscopic sleeve gastrectomy resulted in 57% to 73% excess weight loss at 1 to 7 years, with smaller bougie size (≤36F) significantly predicting greater weight loss.
Why the study?
Does laparoscopic sleeve gastrectomy provide long-term weight loss in patients with morbid obesity?
Cohort (n=1,395)
Does laparoscopic sleeve gastrectomy provide long-term weight loss in patients with morbid obesity?
Laparoscopic sleeve gastrectomy is a safe and durable bariatric procedure, with smaller bougie size predicting greater long-term excess weight loss.
Supports durable weight loss after sleeve gastrectomy; leaves open optimal bougie size for prospective confirmation.
BACKGROUND: To evaluate early, mid and long term efficacy of laparoscopic sleeve gastrectomy as a definitive management of morbid obesity and to study factors that may predict its success. MATERIALS AND METHODS: A retrospective study was conducted by reviewing the database of patients who underwent LSG as a definitive bariatric procedure, from April 2005 to March 2013. Univariate and multivariate analysis were performed. RESULTS: 1395 patients were included in this study. Mean age was 33 years and women:men ratio was 74:26. The mean preoperative BMI was 46 kg/m(2). Operative time was 113 ± 29 min. Reinforcement of staple line was done only in 447 (32%) cases. 11 (0.79%) cases developed postoperative leak, with total number of complications 72 (5.1%) and 0% mortality. Percentage of excess weight loss (%EWL) was 42%, 53%, 61%, 73%, 67%, 61%, 59% and 57% at 6 months, 1-7 years. Remission of diabetes (DM), hypertension (HTN) and hyperlipidaemia (HLP) occurred 69%, 54% and 43% respectively. 56 (4%) patients underwent revision surgery, for insufficient weight loss (n = 37) and severe reflux symptoms (n = 19). Mean follow up was 76 ± 19 (range: 6-103) months. Smaller bougie size and leaving smaller antrum were associated with significant %EWL. Bougie ≤36F remained significant in multivariate analysis. CONCLUSION: This study supports safety, effectiveness and durability of LSG as a sole definitive bariatric procedure. Smaller bougie size and shorter distance from pylorus were associated with significant %EWL.
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Ellatif et al. (2014) conducted a cohort in Morbid obesity (n=1,395). Laparoscopic sleeve gastrectomy was evaluated on Percentage of excess weight loss (%EWL). Laparoscopic sleeve gastrectomy resulted in 57% to 73% excess weight loss at 1 to 7 years, with smaller bougie size (≤36F) significantly predicting greater weight loss.
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