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March 31, 2025Langenbeck s Archives of SurgeryOpen Access

Beyond the decade: unveiling long-term weight and co-morbidity outcomes up to 10 years post laparoscopic sleeve gastrectomy

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Why the study?

Despite its effectiveness, long-term data on the safety and efficacy of laparoscopic sleeve gastrectomy for morbid obesity are sparse.

Does laparoscopic sleeve gastrectomy improve long-term weight loss and comorbidities in patients with morbid obesity?

Population

2982 patients who had laparoscopic sleeve gastrectomy

Design

Observational cohort study via phone interviews and hospital records

Follow-up

Maximum follow-up of 13 years

Authors

SSSalman Al SabahKuwait UniversityEHEliana Al HaddadAmiri HospitalIQIman QadhiAmiri Hospital

Discussion

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Implication

Supports durable LSG benefits at 13 years observationally; extends shorter-term data but leaves open need for RCTs.

Structured PICO

Does laparoscopic sleeve gastrectomy improve long-term weight loss and comorbidities in patients with morbid obesity?

P
Population
2,982 patients with morbid obesity (BMI ≥40 or BMI ≥35 with obesity-related health conditions) who underwent primary laparoscopic sleeve gastrectomy, mean age 34.7 years, 72% female.
I
Intervention
Laparoscopic sleeve gastrectomy (LSG)
O
Outcome
Long-term weight outcomes (BMI, percentage of excess weight loss, percentage of total weight loss), associated health conditions, and complications up to 13 years post-LSGsurrogate

Laparoscopic sleeve gastrectomy provides sustained weight loss and significant resolution of obesity-related comorbidities up to 13 years post-surgery, with low complication rates.

Limitations

  • Self-reported outcomes lack the objectivity of direct clinical assessments
  • High attrition rate over time, with a substantial proportion of patients lost to follow-up beyond 10 years
  • Potential selection bias due to loss to follow-up

Cite This Study

Sabah et al. (2025) studied this question.

synapsesocial.com/papers/6a8349bf23a6192d2aca9e3ehttps://doi.org/10.1007/s00423-025-03680-1
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Gastrointestinal Surgery for Severe Obesity1991 · 2,175 citations
  2. 2Hyperinsulinemic Hypoglycemia with Nesidioblastosis after Gastric-Bypass Surgery2005 · 787 citations
  3. 3Weight Loss and Resolution of Comorbidities After Sleeve Gastrectomy: A Review of Long-Term Results2018 · 43 citations