Acute arterial hypertension during spontaneous angina in patients with fixed coronary stenosis and exertional angina: an associated rather than a triggering phenomenon.

13 consecutive patients with a history of exertional angina and resting angina. 10 patients underwent coronary arteriography and had significant (≥70%) stenosis of at least one major vessel.

Intravenous methoxamine infusion to increase arterial blood pressure and double product (systolic blood pressure x heart rate) to levels higher than those during spontaneous angina, with heart rate maintained spontaneously or by atrial pacing.

Spontaneous episodes of resting angina (within-patient comparison).

Occurrence of chest pain or electrocardiographic changes of myocardial ischemia.surrogate