Population
Anaesthetized cats (33 single afferent sympathetic unmyelinated fibres with left ventricular endings recorded)
Comparison
Mechanical and pharmacological stimuli vs Baseline spontaneous activity
Design
Preclinical
Authors
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Animal data challenge nociceptive-only role for sympathetic afferents; human studies needed to assess cardiovascular control implications.
Unmyelinated cardiac sympathetic afferents are sensitive to mechanical events and participate in continuous cardiovascular neural control, challenging the view that they are purely nociceptive.
Casati et al. (1979) studied this question.
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