Population
Anesthetized, thoracotomized cats
Comparison
Progressive increase in left ventricular… vs Baseline LVEDP
Design
Preclinical
Authors
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Extends LV receptor mechanosensitivity data in cats; leaves open translation to human HF volume regulation.
Left ventricular receptors with non-medullated vagal afferents in cats increase their discharge frequency in response to elevated LVEDP and inotropic stimulation, primarily during systole.
Peter Thorén (1977) studied this question.
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