May 1, 1976Circulation ResearchOpen Access

Mechanical stimuli exciting type A atrial vagal receptors in the cat.

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Structured PICO

Population

Cats anesthetized with sodium pentobarbital, immobilized with gallamine, with open or closed chests

Intervention

Hemodynamic interventions (saline infusion, bleeding, inferior vena cava occlusion), electrical stimulation (right stellate ganglion, left thoracic vagus), atrial pacing, bilateral surgical stellectomy, and propranolol infusion

Comparator

Baseline or pre-intervention conditions

Outcome

Activity (frequency of discharge) of type A right atrial vagal receptors during systole and fillingsurrogate

The systolic discharge of type A atrial vagal receptors is driven by the active tension of atrial muscle contraction rather than just volume changes.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Hypothesis-generating for atrial receptor signaling in animals; leaves open translation to human reflex physiology.

Cite This Study

Recordati et al. (1976) studied this question.

synapsesocial.com/papers/6a8651aebc4cc88ab5833342 https://doi.org/10.1161/01.res.38.5.397

View Full Paper

Ask AI

Bookmark

Mechanical stimuli exciting type A atrial vagal receptors in the cat.

Structured PICO

Discussion

Implication

Cite This Study

Mechanical stimuli exciting type A atrial vagal receptors in the cat.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider