Why the study?
Does pregnancy alter autonomic nervous function and heart rate differently in women with insulin-dependent diabetes compared to nondiabetic women?
Population
n=35 pregnant women, including 25 with insulin-dependent diabetes and 10 nondiabetic women
Comparison
Pregnancy vs Nondiabetic pregnant women
Design
Cohort
Follow-up
throughout pregnancy (each trimester) and postpartum
Authors
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Blunted supine heart rate rise in diabetic pregnancies may reflect autonomic differences; observational data leave open clinical relevance and need for validation.
Does pregnancy alter autonomic nervous function and heart rate differently in women with insulin-dependent diabetes compared to nondiabetic women?
Pregnancy causes a physiological, reversible diminution of heart rate response to deep breathing in both diabetic and nondiabetic women, but the normal pregnancy-induced increase in heart rate is blunted in those with diabetes.
Airaksinen et al. (1987) studied this question.
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