Key result
A combined approach of surgical hemostasis, substitution of blood products, hemodialysis, and rFVIIa safely stopped severe hirudin-induced bleeding in a patient with HIT II and chronic renal failure.
Why the study?
Does a combined approach of surgical hemostasis, blood products, hemodialysis, and rFVIIa stop severe hirudin-induced bleeding in a patient with HIT II and chronic renal failure after cardiac surgery?
Population
1 patient with heparin-induced thrombocytopenia type II and chronic renal failure who suffered from severe…
Design
Case_report
Authors
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Hypothesis-generating for combined hemostasis including rFVIIa in hirudin bleeding; prospective studies needed before clinical adoption.
Case Report (n=1)
Does a combined approach of surgical hemostasis, blood products, hemodialysis, and rFVIIa stop severe hirudin-induced bleeding in a patient with HIT II and chronic renal failure after cardiac surgery?
A combined approach including rFVIIa and hemodialysis may be effective for managing severe hirudin-induced bleeding in cardiac surgery patients with renal failure and HIT II.
Hein et al. (2005) conducted a case report in Heparin-induced thrombocytopenia type II (HIT II) and chronic renal failure with severe hirudin-induced bleeding (n=1). Combined approach of surgical hemostasis, substitution of blood products, hemodialysis, and recombinant factor VIIa (rFVIIa) was evaluated on Bleeding cessation. A combined approach of surgical hemostasis, substitution of blood products, hemodialysis, and rFVIIa safely stopped severe hirudin-induced bleeding in a patient with HIT II and chronic renal failure.
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