Key result
Mean mRS scores in poor-grade SAH patients improved from 4.33 at discharge to 3.31 at 6 months (p<0.001), with 18% and 19% showing further delayed recovery at 6-12 and 12-36 months, respectively.
Cohort (n=88)
Not blinded
No
Absolute Event Rate: 3.31% vs 4.33%
p-value: p=<0.001
A substantial minority of poor-grade SAH patients experience delayed recovery beyond 6 months, suggesting that long-term follow-up is necessary in SAH outcome studies.
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May warrant extended follow-up in poor-grade SAH; leaves open impact on trial endpoints and prognostication.
Wilson et al. (2013) conducted a cohort in Poor-grade aneurysmal subarachnoid hemorrhage (n=88). Time since subarachnoid hemorrhage vs. Hospital discharge was evaluated on Mean aggregate modified Rankin Scale (mRS) score at 6 months (p=<0.001). Mean mRS scores in poor-grade SAH patients improved from 4.33 at discharge to 3.31 at 6 months (p<0.001), with 18% and 19% showing further delayed recovery at 6-12 and 12-36 months, respectively.