The study establishes that pre-translocation-state ribosomes must sample or reside in an intermediate state of tRNA binding independent of the action of EF-G.
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Does not alter clinical practice; leaves open EF-G-independent ribosomal translocation mechanisms for mechanistic studies.
Sharma et al. (2003) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: