Key result
Compared to placebo, high-dose alcohol has a biphasic effect on blood pressure (early -3.5/-1.9 mmHg, late +3.7/+2.4 mmHg) and increases heart rate across all time periods.
Why the study?
Alcohol has both acute and chronic effects on blood pressure, but the acute effect of different alcohol doses on blood pressure and heart rate over time needed quantification.
Does a single dose of alcohol affect blood pressure and heart rate in adults?
Meta-Analysis (n=767)
Does a single dose of alcohol affect blood pressure and heart rate in adults?
Acute alcohol consumption has a biphasic effect on blood pressure, initially lowering it but increasing it after 13-24 hours, while consistently increasing heart rate.
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High-dose alcohol warrants clinical caution for late BP elevation and sustained tachycardia; meta-analysis reinforces its adverse hemodynamic effects.
Sara Tasnim (2019) conducted a meta-analysis in Normal and raised blood pressure (n=767). Single-dose alcohol vs. Placebo was evaluated on Blood pressure and heart rate. Compared to placebo, high-dose alcohol has a biphasic effect on blood pressure (early -3.5/-1.9 mmHg, late +3.7/+2.4 mmHg) and increases heart rate across all time periods.
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