Why the study?
Does a fall in mean arterial pressure correlate with electroencephalographic slowing during open heart surgery?
Does a fall in mean arterial pressure correlate with electroencephalographic slowing during open heart surgery?
A mean arterial pressure of 50 mm Hg or below during open heart surgery is a critical threshold associated with EEG slowing, indicating impaired cerebral blood flow.
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May warrant MAP >50 mm Hg to avoid cerebral hypoperfusion in cardiac surgery; leaves open optimal targets in randomized trials.
Two hundred and fifty-seven recordings of arterial pressure and one hundred and ninety-one recordings of the venous pressure were correlated with incidental, quantitative electroencephalographic findings during open heart surgery in thirty-four patients. A fall in mean arterial pressure to 50 mm of mercury and below was invariably associated with electroencephalographic slowing. This was defined as the “critical” pressure below which the cerebral blood flow falls. EEG is a very sensitive index of impaired cerebral blood flow during open heart surgery.
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Juneja et al. (1972) studied this question.
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