Key result
Higher interleukin-6 levels on admission were independently associated with poor functional outcome at 3 months in patients with lacunar infarction (OR 1.09; 95% CI 1.01-1.26; p=0.003).
Cohort (n=113)
Odds Ratio: 1.09 (95% CI 1.01–1.26)
p-value: p=0.003
High systolic blood pressure and elevated IL-6 levels on admission are predictive of poor functional outcome at 3 months in patients with lacunar infarction.
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IL-6 may aid prognostication in lacunar infarction; hypothesis-generating and requires prospective validation before clinical adoption.
Blanco et al. (2006) conducted a cohort in Lacunar infarction (n=113). Interleukin-6 (IL-6) levels was evaluated on Poor functional outcome (Barthel index <85 at 3 months) (OR 1.09, 95% CI 1.01-1.26, p=0.003). Higher interleukin-6 levels on admission were independently associated with poor functional outcome at 3 months in patients with lacunar infarction (OR 1.09; 95% CI 1.01-1.26; p=0.003).
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