What question did this study set out to answer?

To determine whether promoting single-unit red blood cell transfusions in stable patients reduces overall blood utilization more effectively than adhering to restrictive hemoglobin triggers alone.

February 5, 2017Transfusion

Single‐unit transfusions and hemoglobin trigger: relative impact on red cell utilization

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Authors

WYWilliam W. Yang RTRajiv N. Thakkar EGEric A. Gehrie

Discussion

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Overview

Pre-post study reveals single-unit red cell transfusions reduced blood use more than hemoglobin triggers in community hospitals, indicating single-unit guidelines drive conservation.

Key Points

To determine whether promoting single-unit red blood cell transfusions in stable patients reduces overall blood utilization more effectively than adhering to restrictive hemoglobin triggers alone.
Analyzed monthly blood utilization data across three community hospitals before and after implementing a patient blood management program.
Evaluated the impact of a campaign promoting single-unit transfusions alongside efforts targeting evidence-based hemoglobin triggers of 7 or 8 g/dL.
Used univariate and multivariate analyses to assess independent effects of each intervention on overall red blood cell utilization.
Single-unit transfusions increased from 38.0% to 70.9% (p < 0.0001), while orders using a hemoglobin trigger of ≥8 g/dL decreased from 45.7% to 25.0% (p < 0.0001).
Multivariate analysis showed that the increase in single-unit transfusions was an independent predictor of decreased red cell utilization, whereas hemoglobin triggers of 7 or 8 g/dL were not.
Overall red blood cell utilization decreased by 27.2%, from 0.254 to 0.185 units per patient across all three hospitals (p = 0.0009).

Cite This Study

Yang et al. (2017) studied this question.

synapsesocial.com/papers/6a75bb8a06e84d3015dd8422 https://doi.org/10.1111/trf.14000

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February 5, 2017Transfusion

Single‐unit transfusions and hemoglobin trigger: relative impact on red cell utilization

View Full Paper

Ask AI

Bookmark

Authors

WYWilliam W. Yang RTRajiv N. Thakkar EGEric A. Gehrie

Discussion

Member takes

Overview

Pre-post study reveals single-unit red cell transfusions reduced blood use more than hemoglobin triggers in community hospitals, indicating single-unit guidelines drive conservation.

Key Points

To determine whether promoting single-unit red blood cell transfusions in stable patients reduces overall blood utilization more effectively than adhering to restrictive hemoglobin triggers alone.
Analyzed monthly blood utilization data across three community hospitals before and after implementing a patient blood management program.
Evaluated the impact of a campaign promoting single-unit transfusions alongside efforts targeting evidence-based hemoglobin triggers of 7 or 8 g/dL.
Used univariate and multivariate analyses to assess independent effects of each intervention on overall red blood cell utilization.
Single-unit transfusions increased from 38.0% to 70.9% (p < 0.0001), while orders using a hemoglobin trigger of ≥8 g/dL decreased from 45.7% to 25.0% (p < 0.0001).
Multivariate analysis showed that the increase in single-unit transfusions was an independent predictor of decreased red cell utilization, whereas hemoglobin triggers of 7 or 8 g/dL were not.
Overall red blood cell utilization decreased by 27.2%, from 0.254 to 0.185 units per patient across all three hospitals (p = 0.0009).

Cite This Study

Yang et al. (2017) studied this question.

synapsesocial.com/papers/6a75bb8a06e84d3015dd8422 https://doi.org/10.1111/trf.14000

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