In analysis of NMR spectra, well trained people are not highly variable (within themselves), but there is a potential for variability when different operators are used for analysis. One study has shown similar analytical results between three analysts examining four samples for nine metabolites Another study used five people with multiple rounds of analysis of 18 spectra, to demonstrate good agreement between people for the most common metabolites Furthermore, the experimental group (sampling method) was generally more important than variation between people Despite the consistencies seen between people, it is still recommended that analysis be performed by the same person or group over a single study However, for studies with a large number of samples, or long-term experiments, single operator analysis may not be feasible.
No takes yet. Share an insight, caveat, or question.
Tso V Eisner R (2015) studied this question.