Population
isolated cardiac myocytes (animal and human models)
Design
Review
Authors
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May support n-3 PUFA antiarrhythmic mechanisms in vitro; leaves open clinical translation and efficacy.
n-3 polyunsaturated fatty acids appear to exert antiarrhythmic effects by inhibiting sarcolemmal ion channels and stabilizing the electrical activity of cardiac myocytes.
Leaf et al. (1997) studied this question.
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