Key result
In patients with ischemic mitral regurgitation, the RING+STRING technique increased freedom from MR>II compared to historical controls (94% vs 71%, P=0.01) and promoted reverse remodeling.
Why the study?
Does adjunctive papillary muscle repositioning (STRING) combined with undersized ring annuloplasty (RING) improve freedom from recurrent mitral regurgitation and promote reverse remodeling in patients with ischemic mitral regurgitation and severe leaflet tethering?
Population
Patients with ischemic mitral regurgitation and severe leaflet tethering identified as high-risk for repair…
Comparison
Undersized ring annuloplasty combined with… vs Historical matched control-group.
Design
Cohort
Follow-up
median 26 months
Authors
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May support combined repair in tethered ischemic MR; leaves open need for randomized confirmation before practice change.
Cohort (n=30)
Does adjunctive papillary muscle repositioning (STRING) combined with undersized ring annuloplasty (RING) improve freedom from recurrent mitral regurgitation and promote reverse remodeling in patients with ischemic mitral regurgitation and severe leaflet tethering?
Absolute Event Rate: 94% vs 71%
p-value: p=0.01
The addition of papillary muscle repositioning to undersized ring annuloplasty in patients with ischemic mitral regurgitation and severe leaflet tethering significantly reduces recurrent mitral regurgitation and promotes left ventricular reverse remodeling.
Langer et al. (2009) conducted a cohort in Ischemic mitral regurgitation (n=30). RING+STRING (undersized ring annuloplasty with adjunctive papillary muscle repositioning) vs. Historical matched control-group was evaluated on Freedom from MR>II (p=0.01). In patients with ischemic mitral regurgitation, the RING+STRING technique increased freedom from MR>II compared to historical controls (94% vs 71%, P=0.01) and promoted reverse remodeling.
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