Key result
Ambulatory ST segment depression in elderly men was associated with a higher prevalence of low visuospatial cognitive function compared to those without STDE (84% vs 59%; p=0.014).
Why the study?
Is ambulatory ST segment depression associated with lower cognitive function in healthy elderly men?
Population
88 healthy 81-year-old men from the population study 'Men born in 1914' in Sweden
Comparison
Presence of ST segment depression on ambulatory… vs Absence of ST segment depression
Design
Cross-sectional
Authors
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May link silent ischemia to visuospatial deficits in elderly men; hypothesis-generating and requires prospective validation before practice change.
Cross-Sectional (n=88)
No
Is ambulatory ST segment depression associated with lower cognitive function in healthy elderly men?
Absolute Event Rate: 84% vs 59%
p-value: p=0.014
Ambulatory ST segment depression on 24-hour ECG is associated with lower visuospatial cognitive function in healthy 81-year-old men, suggesting it may be a vascular risk factor for cognitive decline.
Sölve Elmståhl (2009) conducted a cross-sectional in Healthy elderly men (n=88). Ambulatory ST segment depression (STDE) vs. No STDE was evaluated on Low visuospatial cognitive function (p=0.014). Ambulatory ST segment depression in elderly men was associated with a higher prevalence of low visuospatial cognitive function compared to those without STDE (84% vs 59%; p=0.014).
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