Severe craniocerebral injury may be associated with progressive myocardial changes ranging from acute lesions to long-term hypertrophy and fibrosis.
May link craniocerebral trauma to progressive myocardial remodeling; hypothesis-generating case that leaves causal and clinical implications open.
The findings at necropsy in three cases of severe craniocerebral injury associated with unconsciousness are reported with special reference to the histopathological findings in the myocardium. In the first case, death occurred 3 days after the trauma, in the second case 21 days after, and in the third case, 7 years after. Necropsy showed myocardial lesions of recent origin in the first case, stromal condensation in the myocardium in the second, and cardiac hypertrophy with coexisting patchy fibrosis of the myocardium in the third. The relation between craniocerebral injury and subsequent myocardial fibrosis is discussed.
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Jovan Rajs (1976) studied this question.
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