Key result
Increased blood pressure variability in patients with acute ischemic stroke is generally associated with poorer prognosis, including worse functional outcomes, higher mortality, and increased risk of hemorrhagic transformation.
Why the study?
The prognostic importance of blood pressure and blood pressure variability on clinical outcomes after acute ischemic stroke remains unclear.
Does increased blood pressure variability worsen clinical outcomes in patients with acute ischemic stroke?
Does increased blood pressure variability worsen clinical outcomes in patients with acute ischemic stroke?
Increased blood pressure variability across various timeframes after acute ischemic stroke is generally associated with worse clinical outcomes, highlighting it as a potential prognostic marker.
May aid risk stratification in acute ischemic stroke; leaves open whether targeting variability improves outcomes.
Stroke is the second most common cause of mortality. Ischemic stroke is approximately 10 times more common than haemorrhagic stroke. The strongest risk factor for ischemic stroke is hypertension, thus reduction of blood pressure decreases the risk of ischemic stroke. However, the prognostic importance of blood pressure after is unclear. The problem is even more complex considering blood pressure variability (BPV), i.e. continuous changes of blood pressure values. The aim of this review is to discuss the very short-term, short-term, mid-term, and long-term blood pressure variability in the context of clinical outcome in patients after acute ischemic stroke. Most of the studies have shown that increased BPV in ischemic stroke patients is associated with poorer prognosis, however in some of them there was not association between BPV and outcome.
No takes yet. Share an insight, caveat, or question.
Kowalczyk et al. (2020) conducted a review in Acute ischemic stroke. Blood pressure variability was evaluated. Increased blood pressure variability in patients with acute ischemic stroke is generally associated with poorer prognosis, including worse functional outcomes, higher mortality, and increased risk of hemorrhagic transformation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: