Key result
Post-EVAR infrarenal flow models demonstrated decreased peak wall shear stress (p=0.01), pressure drop, and peak velocity (p=0.04) in the iliac arteries compared to physiological flow.
Why the study?
Does endovascular aneurysm repair (EVAR) restore physiological infrarenal blood flow conditions compared to healthy volunteers?
Observational (n=15)
Does endovascular aneurysm repair (EVAR) restore physiological infrarenal blood flow conditions compared to healthy volunteers?
p-value: p=0.01
Computational fluid dynamics reveals that while abdominal hemodynamics converge to normal after EVAR, significant variations persist in the iliac arteries, highlighting areas for endograft design improvement.
Endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms results in redirection of blood through the deployed endograft (EG). Even though EVAR is clinically effective, the absolute flow restoration is not warranted. Our purpose was to compare the physiological with the post-EVAR infrarenal flow conditions. We developed patient-specific models based on computed tomography data of five healthy volunteers and ten patients treated with the Endurant® stent-graft system. Wall shear stress (WSS), helicity, pressure and velocity fields were calculated using computational fluid dynamics. The results showed a decrease of peak WSS on the part of the EG that resides in the iliac arteries, compared to the physiological value (p = 0.01). At the abdominal part, the average helicity seems to increase after EVAR, while at the iliac arteries part, the intensity of helical flow seems physiological. Pressure drop and peak velocity in the iliac arteries part are lower than the physiological values (p = 0.04). The comparison revealed that most hemodynamic properties converge to normal levels at the abdominal part whereas statistically significant variations were observed in the iliac arteries part. The delineation of the differences between physiological and postoperative flow data could pave the way for the improvement of EG designs.
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Raptis et al. (2016) conducted an observational in Abdominal aortic aneurysms (n=15). Endovascular aneurysm repair (EVAR) vs. Physiological flow (healthy volunteers) was evaluated on Wall shear stress (WSS), helicity, pressure and velocity fields (p=0.01). Post-EVAR infrarenal flow models demonstrated decreased peak wall shear stress (p=0.01), pressure drop, and peak velocity (p=0.04) in the iliac arteries compared to physiological flow.
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