Key result
Stem cell-based therapies may alleviate atherosclerosis progression and offer beneficial effects in cardiovascular diseases through paracrine signaling and immunomodulatory effects.
Why the study?
To provide an overview of stem cell-based therapies, delineate their pathophysiological mechanisms in cardiovascular diseases, and highlight key clinical study conclusions.
Stem cell therapies offer potential benefits in cardiovascular diseases, particularly coronary artery disease, primarily through paracrine signaling rather than direct myocardial regeneration.
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Paracrine effects expand stem cell therapeutic scope in heart disease; leaves open rigorous trial validation before clinical adoption.
Papastamos et al. (2023) conducted a review in Cardiovascular diseases, especially coronary artery disease. Stem cell-based therapies was evaluated. Stem cell-based therapies may alleviate atherosclerosis progression and offer beneficial effects in cardiovascular diseases through paracrine signaling and immunomodulatory effects.
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