Why the study?
Does nitrendipine or enalapril reduce left ventricular mass index in patients with non-insulin-dependent diabetes mellitus and hypertension?
Does nitrendipine or enalapril reduce left ventricular mass index in patients with non-insulin-dependent diabetes mellitus and hypertension?
In patients with type 2 diabetes and hypertension, nitrendipine significantly reduced left ventricular mass index compared to placebo, whereas enalapril prevented its progression.
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Nitrendipine reduces LVMI in diabetic hypertension while enalapril stabilizes it; extends evidence for CCB advantage over ACEI on cardiac remodeling.
Gerritsen et al. (1998) studied this question.
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