Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 1, 1995Clinical ScienceOpen Access

Postprandial Sympatho-Adrenal Activity: Its Relation to Metabolic and Cardiovascular Events and to Changes in Meal Frequency

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does a single large meal compared to multiple smaller meals alter postprandial sympatho-adrenal activity and thermogenesis?

Population

Not stated in abstract

Comparison

Single 3.15 MJ mixed meal vs Three 1.05 MJ meals given 30 min apart

Design

Other

Follow-up

120 minutes

Authors

MVMário VazUniversidade de BrasíliaATAndrea TurnerLancashire Teaching Hospitals NHS Foundation TrustBKBronwyn A. KingwellPreventive Cardiology

Discussion

Loading...

Member takes

Overview

Meal frequency does not significantly alter postprandial sympatho-adrenal activity or thermogenesis; hypothesis-generating and should not yet change practice.

Structured PICO

Does a single large meal compared to multiple smaller meals alter postprandial sympatho-adrenal activity and thermogenesis?

P
Population
Not stated in abstract
I
Intervention
Single 3.15 MJ mixed meal
C
Comparator
Three 1.05 MJ meals given 30 min apart
O
Outcome
Sympatho-adrenal activity (whole-body noradrenaline spillover rates, forearm plasma noradrenaline spillover, adrenaline secretion rates) and thermogenesis over 120 minsurrogate

Postprandial sympathetic nervous activation increases after a meal but is not closely related to insulin secretion or thermogenesis, and is not significantly altered by meal frequency.

Cite This Study

Vaz et al. (1995) studied this question.

synapsesocial.com/papers/6a75dfc613a170ef68e697dehttps://doi.org/10.1042/cs0890349
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regional Sympathetic Nervous Activation after a Large Meal in Humans1995 · 101 citations
  2. 2Human Muscle Sympathetic Activity and Cardiac Catecholamine Spillover: No Support for Augmented Sympathetic Noradrenaline Release by Adrenaline Co-Transmission1998 · 17 citations
  3. 3Time course and nature of postprandial haemodynamic changes in normal man1989 · 21 citations
  4. 4Hypoglycemia per se stimulates sympathetic neural as well as adrenomedullary activity, but, unlike the adrenomedullary response, the forearm sympathetic neural response is not reduced after recent hypoglycemia.1999 · 23 citations
  5. 5Adrenaline infusion in man increases muscle sympathetic nerve activity and noradrenaline overflow to plasma1989 · 38 citations