Key result
In patients on maintenance haemodialysis, symptoms of depression were significantly associated with higher serum IL-6 (OR 1.537, P=0.001), more comorbidities, and lower serum albumin.
Population
146 patients on maintenance haemodialysis (65 males, 81 females, mean age 63.8±15.2 years)
Design
Cross-sectional
Authors
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Should not change practice; hypothesis-generating for IL-6 as depression target in hemodialysis.
Cross-Sectional (n=146)
Odds Ratio: 1.537
p-value: p=0.001
In maintenance haemodialysis patients, symptoms of depression are independently associated with higher serum IL-6, lower serum albumin, younger age, and more comorbidities.
Hung et al. (2010) conducted a cross-sectional in maintenance haemodialysis (n=146). Serum IL-6, albumin, and comorbidities was evaluated on Symptoms of depression (BDI≥14) (OR 1.537, p=0.001). In patients on maintenance haemodialysis, symptoms of depression were significantly associated with higher serum IL-6 (OR 1.537, P=0.001), more comorbidities, and lower serum albumin.
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