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December 25, 2013Psychiatry and Clinical Neurosciences

Prevalence of depression symptoms and serum levels of interleukin‐6 in hemodialysis patients

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Population

75 hemodialysis patients

Design

Cross-sectional

Authors

BKBerenice Scaletzky KnuthUniversidade Católica de PelotasVRVinicius Augusto RadtkeUniversidade Católica de PelotasPRPablo Álvarez RochaUniversidad de la República de Uruguay

Discussion

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Implication

Depression in hemodialysis patients was associated with higher IL-6; hypothesis-generating for inflammatory links, should not yet change practice.

Structured PICO

P
Population
75 hemodialysis patients
O
Outcome
Correlation between depression symptoms (measured by Beck Depression Inventory) and serum interleukin-6 (IL-6) levelssurrogate

In hemodialysis patients, depression is highly prevalent and associated with higher IL-6 levels, though symptom severity does not correlate with IL-6 levels.

Cite This Study

Knuth et al. (2013) studied this question.

synapsesocial.com/papers/6a8940ccd42f68325a92cfc4https://doi.org/10.1111/pcn.12130
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of Interleukin-6 on Depression Risk in Dialysis Patients2010 · 46 citations
  2. 2Depressive Symptoms and Proinflammatory Cytokine Levels in Chronic Renal Failure Patients2008 · 37 citations
  3. 3Evaluation of depressive symptoms in patients with chronic renal failure2010 · 42 citations