Analysis of Left Atrioventricular Plane Movement during Diastole in Ischemic Heart Disease.
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Why the study?
Does coronary artery disease alter diastolic left atrioventricular plane displacement compared to healthy subjects?
Population
176 subjects total: 125 patients with exertional angina pectoris, in sinus rhythm, with angiographically…
Design
Cross-sectional, Pulsed Doppler transmitral inflow velocities were read by…
Authors
Discussion
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Implication
Altered diastolic AVPD in CAD may reflect impaired LV filling; leaves open its diagnostic value pending prospective validation.
Structured PICO
Does coronary artery disease alter diastolic left atrioventricular plane displacement compared to healthy subjects?
P
Population
176 subjects total: 125 patients with exertional angina pectoris, in sinus rhythm, with angiographically confirmed coronary artery disease (mean age 58.7 +/- 13.7), and 51 healthy age-matched control subjects. Exclusions: congenital or valvular heart disease, arrhythmias, left ventricular hypertrophy, echocardiographic features of left ventricular aneurysm, and technically inadequate echocardiogram.
O
Outcome
Diastolic left atrioventricular plane displacement (AVPD) properties, specifically mean AVPD in early diastole (E-AVPD), mean AVPD from atrial systole (A-AVPD), and the ratio A-AVPD/E-AVPD measured by M-mode echocardiography.surrogate
In patients with coronary artery disease, diastolic left atrioventricular plane displacement is altered, reflecting reduced early diastolic filling and an increased relative atrial contribution to left ventricular filling.
Limitations
- Echocardiographic study and catheterization were not made simultaneously
- Measurement of left ventricular end-diastolic pressure would have been more precise if a microtype catheter had been used
Cite This Study
Kranidis et al. (1995) studied this question.
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