What question did this study set out to answer?

The research aims to measure global cardiac parameters during a single breath-hold using turboFLASH MR imaging.

June 1, 1999American Journal of Roentgenology

Single breath-hold left ventricular volume measurement by 0.3-sec turbo fast low-angle shot MR imaging.

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Why the study?

Does single-shot turboFLASH MR imaging during a single breath-hold accurately measure ejection fraction compared to radiographic left ventriculography in cardiac patients?

Key Points

The research aims to measure global cardiac parameters during a single breath-hold using turboFLASH MR imaging.
Examined 10 cardiac patients post-cardiac catheterization using T1-weighted turboFLASH MRI.
Acquired 10 slices to measure left ventricular volume in a single breath-hold.
Calculated end-diastolic volume, end-systolic volume, and ejection fraction from MR images.
Ejection fraction from turboFLASH MR images correlates well with left ventriculography measurements (r = 0.87).
Inter-observer variability in ejection fraction calculation was 7.8%; intra-observer variability was 4.7%.
TurboFLASH MR imaging effectively quantifies ejection fraction during a single breath-hold.

Structured PICO

Does single-shot turboFLASH MR imaging during a single breath-hold accurately measure ejection fraction compared to radiographic left ventriculography in cardiac patients?

Population

10 cardiac patients who had undergone cardiac catheterization

Intervention

T1-weighted single-shot turbo fast low-angle shot (turboFLASH) MR imaging with inversion recovery of both end diastole and end systole sequentially accomplished twice in the same R-R interval during a single breath-hold

Comparator

radiographic left ventriculography

Outcome

Correlation of ejection fraction calculated from MR images with data obtained from left ventriculographysurrogate

Single-shot turboFLASH MR imaging during a single breath-hold provides ejection fraction measurements that correlate well with invasive radiographic left ventriculography.

Discussion

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Implication

Supports breath-hold turboFLASH MRI for EF assessment in cardiac patients; leaves open larger prospective validation before clinical adoption.

Cite This Study

Motooka et al. (1999) studied this question.

synapsesocial.com/papers/6a75e6a9db3f4160f98b7004 https://doi.org/10.2214/ajr.172.6.10350309

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Implication

Supports breath-hold turboFLASH MRI for EF assessment in cardiac patients; leaves open larger prospective validation before clinical adoption.