Key result
Cardiac allograft vasculopathy and coronary artery disease developed in 4% (3 of 62) of patients during late follow-up after orthotopic heart transplantation, presenting as a diffuse pathology with limited success from invasive treatments.
Case Report (n=3)
No
Cardiac allograft vasculopathy is a diffuse pathology that can develop in young heart transplant recipients, with limited success from invasive procedures.
Hypothesis-generating for late vasculopathy surveillance; leaves open effective therapies pending larger cohorts.
Cardiac allograft vasculopathy is an accelerated form coronary artery disease that characterized by development of fibrous intimal hyperplasia of all coronary artery. This is a major factor determining long-term survival in heart transplantation. Three (4%) patients were developed coronary artery disease and allograft vasculopathy from orthotopik heart transplantation in 62 patients at our clinic in late follow-up. There were two of the male, one female patients and age 22, 24 and 39, respectively. Because of development in young patients multivessel disease were performed invasive procedures. Women patient was died after diagnosed one year. Two patients continued medical follow-up. Allograft vasculopathy is very diffuse pathology that invasive procedures success is limited in the treatment.
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Çevirme et al. (2012) conducted a case report in Cardiac allograft vasculopathy and coronary artery disease (n=3). Orthotopic heart transplantation was evaluated on Development of cardiac allograft vasculopathy and coronary artery disease. Cardiac allograft vasculopathy and coronary artery disease developed in 4% (3 of 62) of patients during late follow-up after orthotopic heart transplantation, presenting as a diffuse pathology with limited success from invasive treatments.
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