Population
Quiescent human umbilical vein endothelial cells (HUVEC)
Comparison
Long-term incubation with angiotensin II in the… vs Basal state / untreated cells
Design
Preclinical
Follow-up
6 hours
Authors
Loading...
Animal data suggest AT2 protection against AT1 oxidative effects; human studies needed before clinical consideration.
The AT2 receptor functionally antagonizes AT1-induced endothelial superoxide formation via a pathway involving tyrosine phosphatases.
Sohn et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: