This case report highlights an unusual shared morphology of asymmetric septal hypertrophy in identical twins with hypertrophic cardiomyopathy, contrasting with commonly reported heterogeneous expression.
May prompt closer echocardiographic monitoring in monozygotic HCM twins; leaves open modifiers of phenotypic concordance.
We report the case of identical twin sisters, both with hypertrophic cardiomyopathy, and both found to have similar echocardiographic appearances in the form of asymmetric septal hypertrophy. This is unusual, in that published reports commonly describe the heterogeneous expression of this condition in twins.
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Wylie et al. (2002) studied this question.
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