Highlights the importance of early recognition of neuroleptic malignant syndrome to prevent fatal recurrences from continued neuroleptic use.
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Continued neuroleptic use after NMS was associated with fatal recurrence in this case; leaves open optimal prevention strategies for future study.
The clinical features of a fatal case of the neuroleptic malignant syndrome are presented. The fatal episode was a recurrence of the syndrome after a milder episode 3 months earlier. Prescription of neuroleptics was continued unchanged following the latter, as a correct diagnosis was not made at the time. The case emphasises the importance of early recognition of the syndrome and the possibility of spontaneous remission of symptoms despite continued neuroleptic treatment.
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McCarthy et al. (1988) studied this question.
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