Population
Cultured neonatal rat dorsal root ganglion (DRG) neurons
Design
Preclinical
Authors
Loading...
Suggests basis for capsaicin neurotoxicity in sensory neurons; hypothesis-generating and requires validation in mammalian models.
This study provides the first clear demonstration that capsaicin activates a nonselective cation channel in DRG neurons, potentially underlying its neurotoxic effects.
Oh et al. (1996) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: