BMI and Waist Circumference; Cross-Sectional and Prospective Associations with Blood Pressure and Cholesterol in 12-Year-Olds
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Why the study?
Does high BMI or large waist circumference increase blood pressure and adverse cholesterol concentrations in 12-year-old children?
Population
1,432 children at age 12 years from the PIAMA birth cohort in the Netherlands.
Comparison
High body mass index or large waist… vs Normal BMI or normal waist circumference at age…
Design
Cohort
Follow-up
4 years (from age 8 to 12 for prospective analyses)
Authors
Discussion
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Implication
High BMI in 12-year-olds was associated with higher systolic BP; hypothesis-generating for weight normalization benefits, requiring prospective confirmation.
Structured PICO
Does high BMI or large waist circumference increase blood pressure and adverse cholesterol concentrations in 12-year-old children?
P
Population
1,432 children at age 12 years from the PIAMA birth cohort (mean age 12.7 years, 732 girls and 700 boys) in the Netherlands.
I
Intervention
High body mass index (BMI >90th percentile) or large waist circumference (WC >90th percentile) at age 12, as well as persistent high BMI/WC from age 8 to 12.
C
Comparator
Normal BMI or normal waist circumference (≤90th percentile) at age 12, and normal BMI/WC at both ages 8 and 12.
O
Outcome
Blood pressure (systolic and diastolic) and cholesterol concentrations (total, HDL, and total-to-HDL ratio) at age 12.surrogate
High BMI and large waist circumference in 12-year-olds are associated with higher blood pressure and adverse cholesterol profiles, but children who normalize their weight by age 12 do not show these increased risks.
Limitations
- Did not have 8-year anthropometric measures of all children used in cross-sectional analyses
Cite This Study
Bekkers et al. (2012) studied this question.
Topics
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