Why the study?
Patients with chronic kidney disease undergoing renal replacement therapy experience significant psychological changes, warranting investigation into the factors influencing depressive symptoms and quality of life in end-stage renal disease.
What factors influence depressive symptoms and quality of life in patients with end-stage renal disease undergoing renal replacement therapy?
What factors influence depressive symptoms and quality of life in patients with end-stage renal disease undergoing renal replacement therapy?
In patients undergoing renal replacement therapy, shorter dialysis duration and comorbidities are associated with depressive symptoms, highlighting the need for targeted psychological support.
May support routine depression screening in RRT patients; leaves open causal links and intervention trials.
Patients with chronic illnesses, such as those with chronic kidney disease (CKD) that are undergoing renal replacement therapy (RRT), face significant psychological changes. This descriptive cross-sectional research was carried out to investigate the factors that influence depressive symptoms and quality of life (QoL) in patients with end-stage renal disease. Data were collected from 70 participants undergoing RRT using a self-reported questionnaire that included sociodemographic information, depressive symptoms, disease status, and QoL. The Beck Depression Inventory-II (BDI-II) screening scale was used to measure depressive symptoms and the SF-36 (Medical Outcome Survey-Short Form 36) was used to assess QoL. Participants in the study rated their depressive symptoms as 'minimum (44.3%), 'mild' (20%), 'moderate' (21.4%), and 'severe (14.3%). Furthermore, a shorter duration of dialysis and comorbid conditions were significantly associated with the development of depressive symptoms. Patients on RRT for a longer period of time had lower physical activity scores than patients on dialysis for a shorter period of time. Male participants have a higher mental QoL than female participants, suggesting that the mental aspect of renal disease is less impaired than the physical aspect. The findings of this study are expected to increase awareness of RRT therapy targets and enhance patient outcomes.
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Muflih et al. (2021) studied this question.
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