What question did this study set out to answer?

To evaluate predisposing factors, microbiological profiles, and visual outcomes in patients with culture-proven bacterial keratitis.

June 1, 1989Cornea

Factors Influencing Predilection and Outcome in Bacterial Keratitis

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Authors

OGOlafur G. GudmundssonUniversity of Iceland LOL. David OrmerodUniversity of Southern California KKKenneth R. KenyonMassachusetts Eye and Ear Infirmary

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Implication

Retrospective cohort study reveals high rates of predisposing factors and poor visual recovery in bacterial keratitis patients, highlighting the severe burden of corneal infections.

Key Points

To evaluate predisposing factors, microbiological profiles, and visual outcomes in patients with culture-proven bacterial keratitis.
Retrospective review of complete records from 175 patients (176 episodes) with culture-confirmed bacterial keratitis treated over a 4-year period at a single tertiary eye hospital.
Assessment of microbiological culture results, Gram stain correlations, predisposing ocular or iatrogenic risk factors, and post-treatment visual acuity and complication rates.
Gram-positive organisms were identified in 63% of episodes and gram-negative organisms in 40% (15% polymicrobial), with Staphylococcus aureus (28%), coagulase-negative staphylococci (14%), diphtheroids (14%), and Pseudomonas aeruginosa (14%) most frequent.
Predisposing risk factors were identified in 97% of patients, with 50% tied to iatrogenic causes (topical corticosteroids, penetrating keratoplasty, contact lenses) and 16% to ocular trauma.
Although 95% of corneal ulcers resolved with antimicrobial therapy, only 44% of patients achieved visual acuity better than baseline admission levels, and 13% developed major complications.

Cite This Study

Gudmundsson et al. (1989) studied this question.

synapsesocial.com/papers/6a760bf63ddd128930fbd634 https://doi.org/10.1097/00003226-198906000-00007

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Implication

Retrospective cohort study reveals high rates of predisposing factors and poor visual recovery in bacterial keratitis patients, highlighting the severe burden of corneal infections.

Factors Influencing Predilection and Outcome in Bacterial Keratitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Factors Influencing Predilection and Outcome in Bacterial Keratitis

Discussion

Member takes

Implication

Key Points

Cite This Study

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