What type of study is this?

This is a Systematic Review study (also classified as: Meta-Analysis).

September 16, 2025Open Access

Global Burden, Risk Factors, Causative Organisms and Antibiotic Susceptibility Patterns in Bacterial Keratitis

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Authors

RSRohan Bir SinghMassachusetts Eye and Ear Infirmary UPUday Pratap Singh ParmarMassachusetts Eye and Ear Infirmary FWFasika A. WoretaUniformed Services University of the Health Sciences

Discussion

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Implication

Systematic review found bacterial keratitis prevalence at 44% in over 127,000 patients, highlighting trauma and contact lens use as significant risk factors.

Key Points

The pooled prevalence of bacterial keratitis was found to be 44%, indicating a significant global health issue.
Among approximately 25,000 bacterial isolates, 72% were Gram-positive, with Staphylococcus epidermidis being the most prevalent.
Trauma and contact lens wear were identified as major risk factors, affecting 44% and 23% of cases, respectively.
Greater than 95% of Gram-positive bacteria showed susceptibility to vancomycin, while ciprofloxacin susceptibility for Staphylococcus aureus was around 77%.

Cite This Study

Singh et al. (2025) studied this question.

synapsesocial.com/papers/68d4539531b076d99fa591d1 https://doi.org/10.1101/2025.09.15.25335752

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Implication

Systematic review found bacterial keratitis prevalence at 44% in over 127,000 patients, highlighting trauma and contact lens use as significant risk factors.

Global Burden, Risk Factors, Causative Organisms and Antibiotic Susceptibility Patterns in Bacterial Keratitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Global Burden, Risk Factors, Causative Organisms and Antibiotic Susceptibility Patterns in Bacterial Keratitis

Discussion

Member takes

Implication

Key Points

Cite This Study

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