January 1, 1960Circulation ResearchOpen Access

Effects of Experimental Regional Ischemia and Levarterenol on the RS-T Segment and Baseline of Ventricular Surface Electrocardiograms Obtained by Direct-Coupled Amplification

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Population

Dogs (experimental model)

Design

Preclinical

Authors

AKAaron Honori KatcherUniversity of Maryland, Baltimore GPGeorge J. PeirceUniversity of Pennsylvania JSJOHN J. SAŸENHospital of the University of Pennsylvania

Discussion

Member takes

Implication

Supports differentiation of drug from ischemic effects in canine models; leaves open translation to clinical monitoring.

Structured PICO

Population

Dogs (experimental model)

Intervention

Levarterenol administration and experimental regional ischemia

Outcome

Absolute changes of baseline and RS-T segment on the surface of the exposed left ventriclesurrogate

Direct-coupled amplification allows for the differentiation of absolute baseline and RS-T segment changes during ischemia and levarterenol administration in a canine model.

Cite This Study

Katcher et al. (1960) studied this question.

synapsesocial.com/papers/6a760e7cfa1990f79e613c12 https://doi.org/10.1161/01.res.8.1.29

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Effects of Experimental Regional Ischemia and Levarterenol on the RS-T Segment and Baseline of Ventricular Surface Electrocardiograms Obtained by Direct-Coupled Amplification

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effects of Experimental Regional Ischemia and Levarterenol on the RS-T Segment and Baseline of Ventricular Surface Electrocardiograms Obtained by Direct-Coupled Amplification

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider