Why the study?
Epidemiological data have shown that the pattern and profile of diabetes mellitus in India are different, prompting evaluation of body mass composition in underweight type 2 diabetics compared to the normal population.
Does body mass composition differ between underweight type 2 diabetes mellitus patients and healthy underweight controls?
Does body mass composition differ between underweight type 2 diabetes mellitus patients and healthy underweight controls?
Underweight patients with type 2 diabetes have a higher body fat mass and fat percentage compared to healthy underweight controls, which positively correlates with HbA1c levels.
High fat mass in underweight T2DM may signal hidden adiposity; leaves open whether routine body composition assessment improves risk stratification.
Background: Over the past decades, various epidemiological data have shown that the pattern and profile of diabetes mellitus in India are different. The present study was carried out with an aim to study body mass composition in underweight type 2 diabetics and to compare with the normal population. Materials and Methods: The cross-sectional comparative study was conducted between January 2015 and December 2016 and included 60 participants who were selected using the convenient sampling technique. Newly diagnosed patients with type 2 diabetes mellitus and BMI less than 18.5 kg/m2 were considered for the study. Chi square test and Independent student t test were used for finding the statistically significant difference in proportions and between means, respectively; Pearson correlation coefficient was estimated for finding the linear association between two continuous variables. Results: No statistically significant difference was observed between the two groups in terms of age, waist-hip ratio, and BMI. Higher amount of fat mass and percentage were observed among the patients with diabetes as compared to that of the control group (P value < 0.05). However, there was no statistically significant difference between the underweight and the control group patients (P value > 0.05). A significant positive correlation was observed between HbA1c values and body fat mass values (P value < 0.05). Conclusion: Underweight type 2 diabetic patients were found to have high body fat mass as compared to healthy controls and the HbA1C values of the study participants were found to be positively correlated with fat mass.
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Garg et al. (2019) studied this question.
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