Relationship of left atrial strain for subtype diagnosis in acute cerebral infarctions

Akemi YOSHIHARA; Sachiyo Konno; Rika SHIRASAWA; Naotoshi TAKASE; Misaki USUNE; Natsuki EJIRI; Daisuke Tsukui; Hidehiro Takekawa

doi:10.2301/neurosonology.38.5

January 1, 2025NeurosonologyOpen Access

Relationship of left atrial strain for subtype diagnosis in acute cerebral infarctions

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Why the study?

Does left atrial strain (LAS) measurement improve the diagnosis of cardiogenic cerebral embolism in patients with acute ischemic stroke?

Structured PICO

Does left atrial strain (LAS) measurement improve the diagnosis of cardiogenic cerebral embolism in patients with acute ischemic stroke?

P

Population

279 patients admitted within 24 hours of ischemic stroke onset who underwent transthoracic echocardiography within 72 hours. 41 patients had cardiogenic cerebral embolism (CE) related to atrial fibrillation (AF) or paroxysmal AF (PAF), and 238 had non-CE ischemic stroke. Excluded: unanalyzable left atrial strain, moderate or severe valvulopathy, or decreased cardiac function.

I

Intervention

Measurement of left atrial strain (LAS) using two-dimensional speckle tracking echocardiography (2D-STE)

C

Comparator

Measurement of left atrial dimension (LAD) and left atrial volume index (LAVI)

O

Outcome

Diagnostic accuracy of left atrial strain (LAS) for cardiogenic cerebral embolism (CE)surrogate

Limitations

Small sample size of the CE group
Did not evaluate electrocardiography
Did not investigate intra-technician or inter-evaluator error
Unanalyzable patients due to image quality dependence
Two-dimensional evaluation is limited due to complex left atrium shape

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Implication

Left atrial strain measured by two-dimensional speckle tracking echocardiography is a highly accurate imaging biomarker for diagnosing cardiogenic cerebral embolism in patients with acute ischemic stroke.

Abstract

76.3%, and 84.6%, respectively.The odds ratio adjusted for confounding factors was 5.61, 3.49, and 5.43, respectively.These findings suggest that LAS may be useful for the diagnosis of CE.

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Cite This Study

YOSHIHARA et al. (2025) studied this question.

synapsesocial.com/papers/6a761a880327049ca48c59ed https://doi.org/10.2301/neurosonology.38.5

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Relationship of left atrial strain for subtype diagnosis in acute cerebral infarctions

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Relationship of left atrial strain for subtype diagnosis in acute cerebral infarctions

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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