May 2, 2023Scientific Reports70 citationsOpen Access
Investigation of the stent induced deformation on hemodynamic of internal carotid aneurysms by computational fluid dynamics
Structured PICO
Does stent-induced deformation of the parent vessel improve hemodynamic factors in internal carotid artery aneurysms?
P
Population
4 patient-specific internal carotid artery (ICA) aneurysm models (all female, age 34-75) with different ostium sizes and neck vessel angles, selected from the Aneurisk database.
I
Intervention
Stent-induced deformation of the parent vessel (simulated via computational fluid dynamics with one-way Fluid-Solid interaction).
C
Comparator
Original aneurysm geometry (before deformation).
O
Outcome
Hemodynamic factors including wall shear stress (WSS), oscillatory shear index (OSI), mean wall pressure, and mean velocity inside the aneurysms.surrogate
Computational fluid dynamics modeling demonstrates that stent-induced deformation of the parent vessel in internal carotid aneurysms significantly reduces blood velocity and oscillatory shear index, potentially lowering rupture risk.
Abstract
Application of the stent for treatment of the internal carotid artery (ICA) aneurysms has been extensively increased in recent decades. In the present work, stent-induced deformations of the parent vessel of ICA aneurysms are fully investigated. This study tries to visualize blood stream and calculated hemodynamic factors inside the four ICA aneurysms after deformations of parent vessel. For the simulation of the non-Newtonian blood stream, computational fluid dynamic is applied with one-way Fluid-Solid interaction (FSI) approach. Four ICA aneurysms with different ostium sizes and neck vessel angle are selected for this investigation. Wall shear stress on wall of aneurysm is analyzed in two angles of deformation due to application of the stent. Blood flow investigation shows that the deformation of the aneurysm limited blood entrance to the sac region and this decreases the blood velocity and consequently oscillatory shear index (OSI) on the sac wall. It is also observed that the stent-induced deformation is more effective on those cases with extraordinary OSI values on aneurysm wall.