Why the study?
The mechanisms underlying sex differences in AF recurrence following pulmonary vein isolation remain incompletely understood, with non-PV foci and epicardial adipose tissue hypothesized to play a key role.
Does the presence of non-pulmonary vein foci and epicardial adipose tissue predict atrial fibrillation recurrence differently in male and female patients?
Population
304 consecutive patients (75% males) undergoing contrast-enhanced CT and catheter ablation of AF
Comparison
Female vs male patients
Design
Retrospective cohort study
Follow-up
Median of 27 months
Authors
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Sex-specific predictors of AF recurrence after ablation merit consideration in practice; leaves open whether targeted interventions by sex improve outcomes.
Does the presence of non-pulmonary vein foci and epicardial adipose tissue predict atrial fibrillation recurrence differently in male and female patients?
Non-pulmonary vein foci and local epicardial adipose tissue exhibit sex-specific differences and are significant predictors of atrial fibrillation recurrence following catheter ablation.
Sakai et al. (2022) studied this question.
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