Why the study?
Does mass screening for factor V Leiden in asymptomatic women prior to prescribing oral contraceptives improve cost-effective care compared to targeted testing?
Population
Asymptomatic women and teens considering combined hormonal oral contraceptive pills
Comparison
Mass screening for factor V Leiden mutation vs Case-specific testing based on thoughtful…
Design
Review
Authors
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Does not support mass screening; leaves open whether targeted testing improves cost-effectiveness in selected patients.
Does mass screening for factor V Leiden in asymptomatic women prior to prescribing oral contraceptives improve cost-effective care compared to targeted testing?
Mass screening for inherited thrombophilia before prescribing oral contraceptives is not recommended; targeted testing based on clinical history is preferred.
Sass et al. (2002) studied this question.
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