Why the study?
Do organic nitrate vasodilators inhibit platelet function in vitro?
Population
In vitro platelets
Design
Preclinical
Authors
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Should not alter nitrate prescribing in patients; leaves open contribution of platelet inhibition to ischemia benefit.
Do organic nitrate vasodilators inhibit platelet function in vitro?
Organic nitrate vasodilators inhibit platelet aggregation in vitro, suggesting an additional mechanism for their beneficial effects in myocardial ischemia.
Schafer et al. (1980) studied this question.
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